Diagnostic Efficacy of Rapid Immunochromatographic Test in Diagnosis of Dengue Infection
نویسندگان
چکیده
Dengue is a mosquito-borne arboviral disease of grave public health concern worldwide. Early diagnosis and treatment required to reduce morbidity & mortality from complications caused by secondary dengue infection. According WHO, the three main diagnostic modalities for infection are cultivation identification viruses, molecular methods, serology. Whereas virus labour intensive available only in reference laboratories, methods require expensive infrastructure expertise. Serology on other hand not less tedious but also able differentiate between primary dengue. This study was undertaken evaluate efficacy rapid immunochromatographic assay as compared ELISA. The conducted serology section Microbiology laboratory, Sri Guru Ram Das Institute Medical Sciences, Amritsar. Blood samples 429 patients with clinical suspicion were received lab August 2020 December 2020. All subjected ICT ELISA detect NS1 Ag IgM antibodies. majority number cases observed age group 31 40 years while gender-wise ratio 1.43:1 showing male preponderance. Out tested, 156 reactive either antigen or antibodies method. Results NS1Ag results analyzed compared. A sensitivity 81.25% noted specificity 100%. detection comparison shows 82.14% Rapid kits performed at par assays important tools early possible, reducing significantly.
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ژورنال
عنوان ژورنال: Journal of Pure and Applied Microbiology
سال: 2022
ISSN: ['2581-690X', '0973-7510']
DOI: https://doi.org/10.22207/jpam.16.1.42